Paul Zavala-Rivera
Universidad de Sonora, 83000, Hermosillo, México
Title: Micelle encapsulation of ferromagnetic nanoparticles of iron carbide@iron oxide in chitosan
Biography
Biography: Paul Zavala-Rivera
Abstract
In this work, the synthesis and characterization of core@shell nanoparticles of Fe3C/γ-Fe2O3 encapsulated into micelles of sodium dodecylsulfate and oleic acid stabilized with chitosan was developed. The nanoparticles were sonosynthesized at low intensities using iron pentacarbonyl (Fe(CO)5) and oleic acid as iron source and hydrophobic stabilizer, respectively; obtaining a hydrodynamic diameter of 19.71 nm and PDI of 0.134. These nanoparticles were used as the organic phase during the production of a nanoemulsion with sodium dodecylsulfate and water. The final step, involved the stabilization of the nanoemulsion using low molecular weight chitosan solution at 2% in acetic acid by ultrasonication. The nanosystem showed a hydrodynamic diameter of 185.3 nm, a PDI of 0.150 with a superficial charge ζ of 36.7 mV. Due to these physical and chemical properties, it is believed that this type of nanoparticles can be use as theranostic agent.